CATALOG NUMBER: C1905

QUANTITY: 50µL     100µL

DESCRIPTION:

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.

SPECIFICITY:

The Lamin B1 antibody can detects endogenous Lamin B1 protein.

ISOTYPE: IgG1

SPECIES CROSS-REACTIVITY: Human, Rat, Mouse

MOLECULAR WEIGHT: 68KDa

TESTED APPLICATIONS: Western Blot,   IP

APPLICATIONS: WB: 1:2,000-5,000  IP:1:200

*NOTE: Optimal working dilutions must be determined by the end user

STORAGE/HANDING: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Store at -20°C. Do not aliquot the antibody.

WesternBlot

Western blot analysis of 1) HepG2, 2) 293T, with C1905 diluted at 1:5,000.

For research use only; not for use as a diagnostic.

Important Note: During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 100 µL or less, we recommend gently dislodge any liquid in the container^,‘s cap.

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