CATALOG NUMBER: C1906

QUANTITY: 50µL

BACKGROUND:

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.

Source: A Rabbit ployclonal antibody is prepared by immunizing recombinant protein.

SPECIFICITY: The Lamin B1 antibody can detect endogenous Lamin B1 protein.

Reactivity: H-Human  R-Rat  M-Mouse  Mk-Monkey  Dg-Dog  Ch-Chicken  Hm-Hamster  Rb-Rabbit  Sh-Sheep  Pg-Pig

ISOTYPE: IgG

APPLICATIONS:

WB-Western blot IHC-Immunochemistry IF-Immunofluorescence  IP-Immunoprecipitation  ChIP-Chormatin Immunoprecipitation

Recommended dilutions: WB: 1:1,000-3,000    IHC: 1:500-1,000

*NOTE: Optimal working dilutions must be determined by the end user

STORAGE/HANDING: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.. Store at -20°C. Do not aliquot the antibody.

Western blot

Western blot analysis of 1) 293T, 2)Mouse Brain,       Immunohistochemical analysis of

3) Rat Brain tissue with TDY205 diluted at 1:2,000.     paraffin-embedded Mouse Kidney

Tissue using Lamin B1 (TDY205)

Rabbit pAb diluted at 1:500.

For research use only; not for use as a diagnostic.

Important Note: The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Nothing disclosed herein is to be construed as a recommendation to use this product in violation of any patents. The information presented above is believed to be accurate. However, information and product are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. No claims beyond replacement of unacceptable material or refund of purchase price shall be allowed.

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