CATALOG NUMBER: C1816

QUANTITY: 100µL

CONCENTRATION: 0.2 mg/mL

DESCRIPTION:

Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. Beta-catenin also plays an important role in the Wnt signaling pathway.

SPECIFICITY: Human, Mouse, Rat

ISOTYPE: IgG

CELLULAR LOCOLIZATION: Plasma Membrane, Cytosol, Nucleus

MOLECULAR WEIGHT: ~92KDa

TESTED APPLICATIONS: Western Blot, IP, IF

APPLICATIONS: WB: 1:5000;   IF: 1:100;   IP: 5mg for 500 mg of cell lysate.

*NOTE: Optimal working dilutions must be determined by the end user

STORAGE/HANDING: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Store at -20°C. Do not aliquot the antibody.

For research use only; not for use as a diagnostic.

Important Note:

During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 µL or less, we recommend gently dislodge any liquid in the container^,‘s cap.